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Mapping Determinants of Cytokine Signaling via Protein Engineering
Cytokines comprise a large family of secreted ligands that are critical for the regulation of immune homeostasis. Cytokines initiate signaling via dimerization or oligomerization of the cognate receptor subunits, triggering the activation of the Janus Kinases (JAKs)/ signal transducer and activator...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170656/ https://ncbi.nlm.nih.gov/pubmed/30319612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02143 |
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