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Insights into Cytokine–Receptor Interactions from Cytokine Engineering

Cytokines exert a vast array of immunoregulatory actions critical to human biology and disease. However, the desired immunotherapeutic effects of native cytokines are often mitigated by toxicity or lack of efficacy, either of which results from cytokine receptor pleiotropy and/or undesired activatio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Annu Rev Immunol
Prif Awduron: Spangler, Jamie B., Moraga, Ignacio, Mendoza, Juan L., Garcia, K. Christopher
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445396/
https://ncbi.nlm.nih.gov/pubmed/25493332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032713-120211
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