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Insights into Cytokine–Receptor Interactions from Cytokine Engineering

Cytokines exert a vast array of immunoregulatory actions critical to human biology and disease. However, the desired immunotherapeutic effects of native cytokines are often mitigated by toxicity or lack of efficacy, either of which results from cytokine receptor pleiotropy and/or undesired activatio...

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Dades bibliogràfiques
Publicat a:Annu Rev Immunol
Autors principals: Spangler, Jamie B., Moraga, Ignacio, Mendoza, Juan L., Garcia, K. Christopher
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445396/
https://ncbi.nlm.nih.gov/pubmed/25493332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032713-120211
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