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Structural basis for chemokine recognition and activation of a viral G protein–coupled receptor
Chemokines are small proteins that function as immune modulators through activation of chemokine G protein–coupled receptors (GPCRs). Several viruses also encode chemokines and chemokine receptors to subvert the host immune response. How protein ligands activate GPCRs remains unknown. We report the...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445376/ https://ncbi.nlm.nih.gov/pubmed/25745166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa5026 |
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