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High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors

Gene transfer vectors based upon human immunodeficiency virus type 1 (HIV) are widely used in bench research applications and increasingly in clinical investigations, both to introduce novel genes but also to reduce expression of unwanted genes of the host and pathogen. At present, the vast majority...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Hu, Yani, O’Boyle, Kaitlin, Palmer, Donna, Ng, Philip, Sutton, Richard E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444993/
https://ncbi.nlm.nih.gov/pubmed/26029715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.4
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