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High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors

Gene transfer vectors based upon human immunodeficiency virus type 1 (HIV) are widely used in bench research applications and increasingly in clinical investigations, both to introduce novel genes but also to reduce expression of unwanted genes of the host and pathogen. At present, the vast majority...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Hu, Yani, O’Boyle, Kaitlin, Palmer, Donna, Ng, Philip, Sutton, Richard E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444993/
https://ncbi.nlm.nih.gov/pubmed/26029715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.4
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