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High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors

Gene transfer vectors based upon human immunodeficiency virus type 1 (HIV) are widely used in bench research applications and increasingly in clinical investigations, both to introduce novel genes but also to reduce expression of unwanted genes of the host and pathogen. At present, the vast majority...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Methods Clin Dev
Hoofdauteurs: Hu, Yani, O’Boyle, Kaitlin, Palmer, Donna, Ng, Philip, Sutton, Richard E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444993/
https://ncbi.nlm.nih.gov/pubmed/26029715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.4
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