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Gene targeting with a replication-defective adenovirus vector.

Wide application of the gene-targeting technique has been hampered by its low level of efficiency. A replication-defective adenovirus vector was used for efficient delivery of donor DNA in order to bypass this problem. Homologous recombination was selected between a donor neo gene inserted in the ad...

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Detalhes bibliográficos
Main Authors: Fujita, A, Sakagami, K, Kanegae, Y, Saito, I, Kobayashi, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189515/
https://ncbi.nlm.nih.gov/pubmed/7666520
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