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Production and Characterization of Improved Adenovirus Vectors with the E1, E2b, and E3 Genes Deleted

Adenovirus (Ad)-based vectors have great potential for use in the gene therapy of multiple diseases, both genetic and nongenetic. While capable of transducing both dividing and quiescent cells efficiently, Ad vectors have been limited by a number of problems. Most Ad vectors are engineered such that...

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Detalhes bibliográficos
Main Authors: Amalfitano, Andrea, Hauser, Michael A., Hu, Huimin, Serra, Delila, Begy, Catherine R., Chamberlain, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124562/
https://ncbi.nlm.nih.gov/pubmed/9444984
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