Production and Characterization of Improved Adenovirus Vectors with the E1, E2b, and E3 Genes Deleted

Adenovirus (Ad)-based vectors have great potential for use in the gene therapy of multiple diseases, both genetic and nongenetic. While capable of transducing both dividing and quiescent cells efficiently, Ad vectors have been limited by a number of problems. Most Ad vectors are engineered such that...

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Hlavní autoři: Amalfitano, Andrea, Hauser, Michael A., Hu, Huimin, Serra, Delila, Begy, Catherine R., Chamberlain, Jeffrey S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124562/
https://ncbi.nlm.nih.gov/pubmed/9444984
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