Role of Type I Interferon Signaling in Human Metapneumovirus Pathogenesis and Control of Viral Replication

Type I IFN signaling, which is initiated through activation of the alpha interferon receptor (IFNAR), regulates the expression of proteins that are crucial contributors to immune responses. Paramyxoviruses, including human metapneumovirus (HMPV), have evolved mechanisms to inhibit IFNAR signaling, b...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Hastings, Andrew K., Erickson, John J., Schuster, Jennifer E., Boyd, Kelli L., Tollefson, Sharon J., Johnson, Monika, Gilchuk, Pavlo, Joyce, Sebastian, Williams, John V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442394/
https://ncbi.nlm.nih.gov/pubmed/25653440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03275-14
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