Viral acute lower respiratory infections impair CD8(+) T cells through PD-1

Viruses are leading causes of severe acute lower respiratory infections (LRIs). These infections evoke incomplete immunity, as individuals can be repeatedly reinfected throughout life. We report that acute viral LRI causes rapid pulmonary CD8(+) cytotoxic T lymphocyte (T(CD8)) functional impairment...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Erickson, John J., Gilchuk, Pavlo, Hastings, Andrew K., Tollefson, Sharon J., Johnson, Monika, Downing, Melissa B., Boyd, Kelli L., Johnson, Joyce E., Kim, Annette S., Joyce, Sebastian, Williams, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408742/
https://ncbi.nlm.nih.gov/pubmed/22797302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62860
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados