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Acute viral respiratory infection rapidly induces a CD8(+) T cell exhaustion-like phenotype
Acute viral infections typically generate functional effector CD8(+) T cells (T(CD8)) that aid in pathogen clearance. However, during acute viral lower respiratory infection (LRI), lung T(CD8) are functionally impaired and do not optimally control viral replication. T cells also become unresponsive...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733528/ https://ncbi.nlm.nih.gov/pubmed/26401005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403004 |
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