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Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells

Human metapneumovirus (HMPV) is a major cause of morbidity and mortality from acute lower respiratory tract illness, with most individuals seropositive by age five. Despite the presence of neutralizing antibodies, secondary infections are common and can be severe in young, elderly, and immunocomprom...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Hastings, Andrew K., Gilchuk, Pavlo, Joyce, Sebastian, Williams, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875773/
https://ncbi.nlm.nih.gov/pubmed/27105560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.04.034
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