Role of Type I Interferon Signaling in Human Metapneumovirus Pathogenesis and Control of Viral Replication

Type I IFN signaling, which is initiated through activation of the alpha interferon receptor (IFNAR), regulates the expression of proteins that are crucial contributors to immune responses. Paramyxoviruses, including human metapneumovirus (HMPV), have evolved mechanisms to inhibit IFNAR signaling, b...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hastings, Andrew K., Erickson, John J., Schuster, Jennifer E., Boyd, Kelli L., Tollefson, Sharon J., Johnson, Monika, Gilchuk, Pavlo, Joyce, Sebastian, Williams, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442394/
https://ncbi.nlm.nih.gov/pubmed/25653440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03275-14
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