Role of Type I Interferon Signaling in Human Metapneumovirus Pathogenesis and Control of Viral Replication

Type I IFN signaling, which is initiated through activation of the alpha interferon receptor (IFNAR), regulates the expression of proteins that are crucial contributors to immune responses. Paramyxoviruses, including human metapneumovirus (HMPV), have evolved mechanisms to inhibit IFNAR signaling, b...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Hastings, Andrew K., Erickson, John J., Schuster, Jennifer E., Boyd, Kelli L., Tollefson, Sharon J., Johnson, Monika, Gilchuk, Pavlo, Joyce, Sebastian, Williams, John V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442394/
https://ncbi.nlm.nih.gov/pubmed/25653440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03275-14
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