Phosphorylation of Human Metapneumovirus M2-1 Protein Upregulates Viral Replication and Pathogenesis

Human metapneumovirus (hMPV) is a major causative agent of upper- and lower-respiratory-tract infections in infants, the elderly, and immunocompromised individuals worldwide. Like all pneumoviruses, hMPV encodes the zinc binding protein M2-1, which plays important regulatory roles in RNA synthesis....

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Cai, Hui, Zhang, Yu, Lu, Mijia, Liang, Xueya, Jennings, Ryan, Niewiesk, Stefan, Li, Jianrong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984647/
https://ncbi.nlm.nih.gov/pubmed/27252537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-16
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