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Rational Design of Human Metapneumovirus Live Attenuated Vaccine Candidates by Inhibiting Viral mRNA Cap Methyltransferase

The paramyxoviruses human respiratory syncytial virus (hRSV), human metapneumovirus (hMPV), and human parainfluenza virus type 3 (hPIV3) are responsible for the majority of pediatric respiratory diseases and inflict significant economic loss, health care costs, and emotional burdens. Despite major e...

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Detalhes bibliográficos
Main Authors: Zhang, Yu, Wei, Yongwei, Zhang, Xiaodong, Cai, Hui, Niewiesk, Stefan, Li, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178811/
https://ncbi.nlm.nih.gov/pubmed/25056882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00876-14
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