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Multiple inhibitory pathways contribute to lung CD8(+) T cell impairment and protect against immunopathology during acute viral respiratory infection
Viruses are frequent causes of lower respiratory infection (LRI). Programmed cell death-1 (PD-1) signaling contributes to pulmonary CD8(+) T cell (T(CD8)) functional impairment during acute viral LRI, but the role of T(CD8) impairment in viral clearance and immunopathology is unclear. We now find th...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933524/ https://ncbi.nlm.nih.gov/pubmed/27259857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502115 |
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