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Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis
Mass spectrometry (MS)-based proteomics has become the most utilized tool to characterize histone post-translational modifications (PTMs). Since histones are highly enriched in lysine and arginine residues, lysine derivatization has been developed to prevent the generation of short peptides (3-6 res...
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| Wydane w: | Proteomics |
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| Główni autorzy: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441824/ https://ncbi.nlm.nih.gov/pubmed/25641854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400483 |
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