Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis

Mass spectrometry (MS)-based proteomics has become the most utilized tool to characterize histone post-translational modifications (PTMs). Since histones are highly enriched in lysine and arginine residues, lysine derivatization has been developed to prevent the generation of short peptides (3-6 res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proteomics
Prif Awduron: Sidoli, Simone, Yuan, Zuo-Fei, Lin, Shu, Karch, Kelly, Wang, Xiaoshi, Bhanu, Natarajan, Arnaudo, Anna M., Britton, Laura-Mae, Cao, Xing-Jun, Gonzales-Cope, Michelle, Han, Yumiao, Liu, Shichong, Molden, Rosalynn C., Wein, Samuel, Afjehi-Sadat, Leila, Garcia, Benjamin A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441824/
https://ncbi.nlm.nih.gov/pubmed/25641854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400483
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