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Quantifying the Tendency of Therapeutic Target Proteins to Bind Promiscuous or Selective Compounds
The ability of target proteins to bind structurally diverse compounds and compounds with different degrees of promiscuity (multi-target activity) was systematically assessed on the basis of currently available activity data and target annotations. Intuitive first- and second-order target promiscuity...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441477/ https://ncbi.nlm.nih.gov/pubmed/26000736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126838 |
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