The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis

Leishmania spp. are trypanosomatid parasites that replicate intracellularly in macrophages, causing serious human morbidity and mortality throughout the world. Trypanosomatid protozoa cannot synthesize heme, so must acquire this essential cofactor from their environment. Earlier studies identified L...

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Bibliografski detalji
Izdano u:PLoS Negl Trop Dis
Glavni autori: Renberg, Rebecca L., Yuan, Xiaojing, Samuel, Tamika K., Miguel, Danilo C., Hamza, Iqbal, Andrews, Norma W., Flannery, Andrew R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441390/
https://ncbi.nlm.nih.gov/pubmed/26001191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003804
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