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Heme Uptake Mediated by LHR1 Is Essential for Leishmania amazonensis Virulence

The protozoan parasite Leishmania amazonensis is a heme auxotroph and must acquire this essential factor from the environment. Previous studies showed that L. amazonensis incorporates heme through the transmembrane protein LHR1 (Leishmania Heme Response 1). LHR1-null promastigotes were not viable, s...

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Detaylı Bibliyografya
Asıl Yazarlar: Miguel, Danilo C., Flannery, Andrew R., Mittra, Bidyottam, Andrews, Norma W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811768/
https://ncbi.nlm.nih.gov/pubmed/23876801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00687-13
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