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Ascorbate-Dependent Peroxidase (APX) from Leishmania amazonensis Is a Reactive Oxygen Species-Induced Essential Enzyme That Regulates Virulence

The molecular mechanisms underlying biological differences between two Leishmania species that cause cutaneous disease, L. major and L. amazonensis, are poorly understood. In L. amazonensis, reactive oxygen species (ROS) signaling drives differentiation of nonvirulent promastigotes into forms capabl...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Xiang, Lucia, Laranjeira-Silva, Maria Fernanda, Maeda, Fernando Y., Hauzel, Jason, Andrews, Norma W., Mittra, Bidyottam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867856/
https://ncbi.nlm.nih.gov/pubmed/31527128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00193-19
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