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Ascorbate-Dependent Peroxidase (APX) from Leishmania amazonensis Is a Reactive Oxygen Species-Induced Essential Enzyme That Regulates Virulence

The molecular mechanisms underlying biological differences between two Leishmania species that cause cutaneous disease, L. major and L. amazonensis, are poorly understood. In L. amazonensis, reactive oxygen species (ROS) signaling drives differentiation of nonvirulent promastigotes into forms capabl...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Xiang, Lucia, Laranjeira-Silva, Maria Fernanda, Maeda, Fernando Y., Hauzel, Jason, Andrews, Norma W., Mittra, Bidyottam
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867856/
https://ncbi.nlm.nih.gov/pubmed/31527128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00193-19
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