Ascorbate-Dependent Peroxidase (APX) from Leishmania amazonensis Is a Reactive Oxygen Species-Induced Essential Enzyme That Regulates Virulence

The molecular mechanisms underlying biological differences between two Leishmania species that cause cutaneous disease, L. major and L. amazonensis, are poorly understood. In L. amazonensis, reactive oxygen species (ROS) signaling drives differentiation of nonvirulent promastigotes into forms capabl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Xiang, Lucia, Laranjeira-Silva, Maria Fernanda, Maeda, Fernando Y., Hauzel, Jason, Andrews, Norma W., Mittra, Bidyottam
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867856/
https://ncbi.nlm.nih.gov/pubmed/31527128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00193-19
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