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Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

Trypanosomatid protozoan parasites lack a functional heme biosynthetic pathway, so must acquire heme from the environment to survive. However, the molecular pathway responsible for heme acquisition by these organisms is unknown. Here we show that L. amazonensis LHR1, a homolog of the C. elegans plas...

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Detalhes bibliográficos
Main Authors: Huynh, Chau, Yuan, Xiaojing, Miguel, Danilo C., Renberg, Rebecca L., Protchenko, Olga, Philpott, Caroline C., Hamza, Iqbal, Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395602/
https://ncbi.nlm.nih.gov/pubmed/22807677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002795
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