The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis

Leishmania spp. are trypanosomatid parasites that replicate intracellularly in macrophages, causing serious human morbidity and mortality throughout the world. Trypanosomatid protozoa cannot synthesize heme, so must acquire this essential cofactor from their environment. Earlier studies identified L...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Renberg, Rebecca L., Yuan, Xiaojing, Samuel, Tamika K., Miguel, Danilo C., Hamza, Iqbal, Andrews, Norma W., Flannery, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441390/
https://ncbi.nlm.nih.gov/pubmed/26001191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003804
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