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A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes

Infection of mammalian hosts with Leishmania amazonensis depends on the remarkable ability of these parasites to replicate within macrophage phagolysosomes. A critical adaptation for survival in this harsh environment is an efficient mechanism for gaining access to iron. In this study, we identify a...

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Detalhes bibliográficos
Main Authors: Huynh, Chau, Sacks, David L., Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118100/
https://ncbi.nlm.nih.gov/pubmed/17000865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060559
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