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Leishmania-Mediated Inhibition of Iron Export Promotes Parasite Replication in Macrophages
Leishmania parasites infect macrophages, cells that play an important role in organismal iron homeostasis. By expressing ferroportin, a membrane protein specialized in iron export, macrophages release iron stored intracellularly into the circulation. Iron is essential for the intracellular replicati...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907422/ https://ncbi.nlm.nih.gov/pubmed/24497831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003901 |
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