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Comparative analysis of resistant and susceptible macrophage gene expression response to Leishmania major parasite

BACKGROUND: Leishmania are obligated intracellular pathogens that replicate almost exclusively in macrophages. The outcome of infection depends largely on parasite pathogenicity and virulence but also on the activation status and genetic background of macrophages. Animal models are essential for a b...

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Detalhes bibliográficos
Main Authors: Rabhi, Imen, Rabhi, Sameh, Ben-Othman, Rym, Aniba, Mohamed Radhouane, Trentin, Bernadette, Piquemal, David, Regnault, Béatrice, Guizani-Tabbane, Lamia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007596/
https://ncbi.nlm.nih.gov/pubmed/24148319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-723
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