OptiType: precision HLA typing from next-generation sequencing data

Motivation: The human leukocyte antigen (HLA) gene cluster plays a crucial role in adaptive immunity and is thus relevant in many biomedical applications. While next-generation sequencing data are often available for a patient, deducing the HLA genotype is difficult because of substantial sequence s...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Szolek, András, Schubert, Benjamin, Mohr, Christopher, Sturm, Marc, Feldhahn, Magdalena, Kohlbacher, Oliver
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441069/
https://ncbi.nlm.nih.gov/pubmed/25143287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu548
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