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OptiType: precision HLA typing from next-generation sequencing data
Motivation: The human leukocyte antigen (HLA) gene cluster plays a crucial role in adaptive immunity and is thus relevant in many biomedical applications. While next-generation sequencing data are often available for a patient, deducing the HLA genotype is difficult because of substantial sequence s...
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| Опубликовано в: : | Bioinformatics |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441069/ https://ncbi.nlm.nih.gov/pubmed/25143287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu548 |
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