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Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

BACKGROUND: The adaptive immune response intrinsically depends on hypervariable human leukocyte antigen (HLA) genes. Concomitantly, correct HLA phenotyping is crucial for successful donor-patient matching in organ transplantation. The cost and technical limitations of current laboratory techniques,...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Matey-Hernandez, Maria Luisa, Brunak, Søren, Izarzugaza, Jose M. G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019707/
https://ncbi.nlm.nih.gov/pubmed/29940840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2239-6
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