OptiType: precision HLA typing from next-generation sequencing data

Motivation: The human leukocyte antigen (HLA) gene cluster plays a crucial role in adaptive immunity and is thus relevant in many biomedical applications. While next-generation sequencing data are often available for a patient, deducing the HLA genotype is difficult because of substantial sequence s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Szolek, András, Schubert, Benjamin, Mohr, Christopher, Sturm, Marc, Feldhahn, Magdalena, Kohlbacher, Oliver
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Original Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441069/
https://ncbi.nlm.nih.gov/pubmed/25143287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu548
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