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Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells

Covalent binding of squalene to siRNA has already been shown to be an interesting way of delivering siRNA in vivo. Whether squalene derivatives could also be used to deliver siRNA in cells without covalent binding similar to usual transfection with cationic lipids is the question addressed in this a...

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Bibliografski detalji
Izdano u:Nucleic Acid Ther
Glavni autori: Bertrand, Jean-Rémi, Lucas, Claire, Pham, Ngoc Minh, Durieu, Catherine, Couvreur, Patrick, Malvy, Claude Paul, Desmaële, Didier
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440994/
https://ncbi.nlm.nih.gov/pubmed/25894614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0504
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