Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells

Covalent binding of squalene to siRNA has already been shown to be an interesting way of delivering siRNA in vivo. Whether squalene derivatives could also be used to deliver siRNA in cells without covalent binding similar to usual transfection with cationic lipids is the question addressed in this a...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acid Ther
Hauptverfasser: Bertrand, Jean-Rémi, Lucas, Claire, Pham, Ngoc Minh, Durieu, Catherine, Couvreur, Patrick, Malvy, Claude Paul, Desmaële, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440994/
https://ncbi.nlm.nih.gov/pubmed/25894614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0504
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