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Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

RET/PTC3 junction oncogene is typical of radiation-induced childhood papillary thyroid carcinoma (PTC) with a short latency period. Since, RET/PTC3 is only present in the tumour cells, thus represents an interesting target for specific therapy by small interfering RNA (siRNA). Our aim is to demonstr...

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書誌詳細
主要な著者: Ali, Hafiz Muhammad, Urbinati, Giorgia, Chapuis, Hubert, DesmaEle, Didier, Bertrand, Jean-Rémi, Couvreur, Patrick, Massaad-Massade, Liliane
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997558/
https://ncbi.nlm.nih.gov/pubmed/24759995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095964
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