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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer

TMPRSS2-ERG junction oncogene is present in more than 50% of patients with prostate cancer and its expression is frequently associated with poor prognosis. Our aim is to achieve gene knockdown by siRNA TMPRSS2-ERG and then to assess the biological consequences of this inhibition. First, we designed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Urbinati, Giorgia, Ali, Hafiz Muhammad, Rousseau, Quentin, Chapuis, Hubert, Desmaële, Didier, Couvreur, Patrick, Massaad-Massade, Liliane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416711/
https://ncbi.nlm.nih.gov/pubmed/25933120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125277
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