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Structural Features Facilitating Tumor Cell Targeting and Internalization by Bleomycin and Its Disaccharide
[Image: see text] We have shown previously that the bleomycin (BLM) carbohydrate moiety can recapitulate the tumor cell targeting effects of the entire BLM molecule, that BLM itself is modular in nature consisting of a DNA-cleaving aglycone which is delivered selectively to the interior of tumor cel...
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| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2015
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440614/ https://ncbi.nlm.nih.gov/pubmed/25905565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00277 |
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