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The Carbamoylmannose Moiety of Bleomycin Mediates Selective Tumor Cell Targeting

[Image: see text] Recently, we reported that both bleomycin (BLM) and its disaccharide, conjugated to the cyanine dye Cy5**, bound selectively to cancer cells. Thus, the disaccharide moiety alone recapitulates the tumor cell targeting properties of BLM. Here, we demonstrate that the conjugate of the...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Chandrabali, Yu, Zhiqiang, Rishel, Michael J., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038340/
https://ncbi.nlm.nih.gov/pubmed/24811347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500482q
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