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The Disaccharide Moiety of Bleomycin Facilitates Uptake by Cancer Cells
[Image: see text] The disaccharide moiety is responsible for the tumor cell targeting properties of bleomycin (BLM). While the aglycon (deglycobleomycin) mediates DNA cleavage in much the same fashion as bleomycin, it exhibits diminished cytotoxicity in comparison to BLM. These findings suggested th...
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| Glavni autori: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183664/ https://ncbi.nlm.nih.gov/pubmed/25184545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja507255g |
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