Modified Bleomycin Disaccharides Exhibiting Improved Tumor Cell Targeting

[Image: see text] The bleomycins (BLMs) are a family of antitumor antibiotics used clinically for anticancer chemotherapy. Their antitumor selectivity derives at least in part from their ability to target tumor cells, a property that resides in the carbohydrate moiety of the antitumor agent. In earl...

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Pubblicato in:Biochemistry
Autori principali: Madathil, Manikandadas M., Bhattacharya, Chandrabali, Yu, Zhiqiang, Paul, Rakesh, Rishel, Michael J., Hecht, Sidney M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222530/
https://ncbi.nlm.nih.gov/pubmed/25272367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501102z
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