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Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor
The constitutive androstane receptor (CAR, NR1I3) plays a key role in governing the transcription of numerous hepatic genes that involve xenobiotic metabolism/clearance, energy homeostasis, and cell proliferation. Thus, identification of novel human CAR (hCAR) modulators may not only enhance early p...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438668/ https://ncbi.nlm.nih.gov/pubmed/25993555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10405 |
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