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Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate

The DNA replication checkpoint (DRC) monitors and responds to stalled replication forks to prevent genomic instability. How core replication factors integrate into this phosphorylation cascade is incompletely understood. Here, through analysis of a unique mcm allele targeting a specific ATPase activ...

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Publicat a:Mol Cell Biol
Autors principals: Tsai, Feng-Ling, Vijayraghavan, Sriram, Prinz, Joseph, MacAlpine, Heather K., MacAlpine, David M., Schwacha, Anthony
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438241/
https://ncbi.nlm.nih.gov/pubmed/25870112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01357-14
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