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Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate
The DNA replication checkpoint (DRC) monitors and responds to stalled replication forks to prevent genomic instability. How core replication factors integrate into this phosphorylation cascade is incompletely understood. Here, through analysis of a unique mcm allele targeting a specific ATPase activ...
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發表在: | Mol Cell Biol |
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Main Authors: | , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Society for Microbiology
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438241/ https://ncbi.nlm.nih.gov/pubmed/25870112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01357-14 |
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