Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs

Fragments of the mitochondrial genome released into the systemic circulation after mechanical trauma, termed mitochondrial DNA damage-associated molecular patterns (mtDNA DAMPs), are thought to mediate the systemic inflammatory response syndrome. The close association between circulating mtDNA DAMP...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kuck, Jamie L., Obiako, Boniface O., Gorodnya, Olena M., Pastukh, Viktor M., Kua, Justin, Simmons, Jon D., Gillespie, Mark N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437009/
https://ncbi.nlm.nih.gov/pubmed/25795724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00015.2015
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