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Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences
Lung tissue from COPD patients displays oxidative DNA damage. The present study determined whether oxidative DNA damage was randomly distributed or whether it was localized in specific sequences in either the nuclear or mitochondrial genomes. The DNA damage-specific histone, gamma-H2AX, was detected...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107697/ https://ncbi.nlm.nih.gov/pubmed/21660298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S15922 |
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