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Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure
Application of hydrostatic pressure shifts protein conformational equilibria in a direction to reduce the volume of the system. A current view is that the volume reduction is dominated by elimination of voids or cavities in the protein interior via cavity hydration, although an alternative mechanism...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4434698/ https://ncbi.nlm.nih.gov/pubmed/25918400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506505112 |
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