Nitrostyrene derivatives act as RXRα ligands to inhibit TNFα activation of NFκB

Retinoid X receptor alpha (RXRα) and its N-terminally truncated version - tRXRα are widely implicated in cancer development and represent intriguing targets for cancer prevention and treatment. Successful manipulation of RXRα and tRXRα requires the identification of their modulators that could produ...

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Publicado no:Cancer Res
Main Authors: Zeng, Zhiping, Sun, Zhe, Huang, Mingfeng, Zhang, Weidong, Liu, Jie, Chen, Liqun, Chen, Fan, Zhou, Yuqi, Lin, Jiacheng, Huang, Fengyu, Xu, Lin, Zhuang, Zixing, Guo, Shangjie, Alitongbieke, Gulimiran, Xie, Guobin, Xu, Yang, Lin, Bingzhen, Cao, Xihua, Su, Ying, Zhang, Xiao-kun, Zhou, Hu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433622/
https://ncbi.nlm.nih.gov/pubmed/25795708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2435
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