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Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation
The epithelial Na(+) channel (ENaC) functions as a pathway for Na(+) absorption in the kidney and lung, where it is crucial for Na(+) homeostasis and blood pressure regulation. ENaC is regulated in part through signaling pathways that control the ubiquitination state of ENaC lysines. A defect in ubi...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432271/ https://ncbi.nlm.nih.gov/pubmed/25787079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.635540 |
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